KIF3A Rabbit pAb, PE-Cy5.5 conjugated(bs-21397R-PE-Cy5.5)-100ul

KIF3A Rabbit pAb, PE-Cy5.5 con

jugated(bs-21397R-PE-Cy5.5)-100ul
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  • ￥2980
  • Bioss已认证
  • bs-21397R-PE-Cy5.5
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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北京博奥森生物技术有限公司
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    • 规格：

      100ul

    产品编号bs-21397R-PE-Cy5.5
    英文名称KIF3A Rabbit pAb, PE-Cy5.5 conjugated
    中文名称PE-Cy5.5标记的驱动蛋白家族蛋白3抗体
    英文别名KIF 3; KIF-3; KIF 3A; KIF-3A; KIF3; Kif3a; KIF3A_HUMAN; Kifl; kinesin family member 3A; Kinesin family protein 3; Kinesin family protein 3A; Kinesin like protein KIF 3A; Kinesin like protein KIF3A; Kinesin-like protein KIF3A; Kns3; Microtubule plus end directed kinesin motor 3A; Microtubule plus end-directed kinesin motor 3A.
    产品应用IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human KIF3A
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Neuroscience > Neurotransmitter > Transporters > Other Transporters

    Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Motor Proteins > Kinesin

    Signal Transduction > Protein Trafficking > Vesicle Transport > Adapters

    Stem Cells > Signaling Pathways > Wnt > Surface Molecules

    亚基Belongs to the kinesin-like protein family. Kinesin II subfamily._x000D_ Contains 1 kinesin-motor domain.
    亚细胞定位 Cytoplasm, cytoskeleton (Probable). Cell projection, cilium (By similarity).
    相似性Belongs to the kinesin-like protein family. Kinesin II subfamily.
    Contains 1 kinesin-motor domain._x000D_
    功能Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料The kinesins constitute a large family of microtubule-dependent motor proteins which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. Members of the heterotrimeric kinesin II family of microtubule associated motors generally contain two different motor subunits from the KIF3 family, which includes KIF3A, B and C. KIF3 isoforms mediate anterograde transport of membrane bound organelles in neurons and melanosomes, transport between the endoplasmic reticulum and the Golgi, and transport of protein complexes within cilia and flagella required for their morphogenesis. KIF3A may influence neurogenesis at the level of embryonic cellular events, where the asymmetry of the genetic control circuit controlling left-right (L-R) axis determination is defined. Loss of KIF3A function in mice photoreceptors causes apoptotic cell death, suggesting that kinesin II mediated transport is required for proper cell fate.

     

    应用推荐稀释比例
    {IF}{1:100-500}

     

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