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- Bioss
- bs-4238R-BF594
- 2025年09月30日
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100ul
| 产品编号 | bs-4238R-BF594 |
| 英文名称 | ARNT2 Rabbit pAb, BF594 conjugated |
| 中文名称 | BF594标记的芳香烃受体核转录蛋白2抗体 |
| 英文别名 | ARNT protein 2; Aryl hydrocarbon receptor nuclear translocator 2.ARNT2_HUMAN |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human ARNT2 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cancer Metabolism > Response to hypoxia Epigenetics and Nuclear Signaling > Transcription > Polymerase associated factors > Pol II Transcription Epigenetics and Nuclear Signaling > Transcription > Transcription Factors Metabolism > Pathways and Processes > Metabolism processes > Hypoxia Metabolism > Types of disease > Cancer Neuroscience > Neurology process > Neural Signal Transduction |
| 亚基 | Efficient DNA binding requires dimerization with another bHLH protein. Heterodimer with the aryl hydrocarbon receptor (AHR) or the SIM1 protein. Interacts with TACC3. |
| 亚细胞定位 | Nucleus (Potential). |
| 相似性 | Contains 1 bHLH (basic helix-loop-helix) domain. Contains 1 PAC (PAS-associated C-terminal) domain. Contains 2 PAS (PER-ARNT-SIM) domains._x000D_ |
| 功能 | Specifically recognizes the xenobiotic response element (XRE). |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | ARNT2 is a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. It acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, ARNT2 protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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ARNT2 Rabbit pAb, BF594 conjugated(bs-4238R-BF594)-100ul
￥2980
