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- bs-8650R-Cy5
- 2025年09月30日
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100ul
| 产品编号 | bs-8650R-Cy5 |
| 英文名称 | T2R38 Rabbit pAb, Cy5 conjugated |
| 中文名称 | Cy5标记的味觉感受器蛋白T2R38抗体 |
| 英文别名 | PTC; PTC bitter taste receptor; TAS2R38; T2R38; T2R61; taste receptor, type 2, member 38; T2R38_HUMAN. |
| 产品应用 | ICC/IF=1:50-200, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human T2R38/TAS2R38 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Neuroscience > Neurotransmission > Receptors / Channels > GPCR > More GPCR Neuroscience > Sensory System > Taste system Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR |
| 亚细胞定位 | Membrane; Multi-pass membrane protein. |
| 组织特异性 | Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. |
| 相似性 | Belongs to the G-protein coupled receptor T2R family. |
| 功能 | TAS2R38 is gustducin-linked and may play a role in the perception of bitterness and in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The sense of taste is essential for the survival of organisms. For example, the ability to identify sweet-tasting foods enables animals to seek out food with high nutritive value, whereas the ability to identify bitter substances enables them to avoid the ingestion of potentially harmful substances. A family of integral membrane proteins are involved in taste perception and include T1R, which is involved in sweet taste perception and T2R, which is involved in bitter taste perception. Both types of taste receptors couple to various G proteins to initiate signal transduction cascades. Specifically, T2R38 is expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Variations in T2R38 are associated with the ability to taste the bitter chemical phenylthiocarbamide (PTC), also called thiourea tasting. |
| 应用 | 推荐稀释比例 |
| {ICC/IF} | {1:50-200} |
| {IF} | {1:100-500} |
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T2R38 Rabbit pAb, Cy5 conjugated(bs-8650R-Cy5)-100ul
￥2980
