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- bs-6526R-FITC
- 2025年10月15日
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100ul
| 产品编号 | bs-6526R-FITC |
| 英文名称 | CD39L4 Rabbit pAb, FITC conjugated |
| 中文名称 | FITC标记的原癌基因CD39样蛋白4/ENTPD5抗体 |
| 英文别名 | CD39 like 4; AI196558; AI987697; CD39 antigen like 4; CD39 antigen-like 4; CD39 like 4; CD39L4; Ectonucleoside triphosphate diphosphohydrolase 5; ENTP5_HUMAN; Entpd5; ER UDPase; ER-UDPase; GDPase ENTPD5; Guanosine-diphosphatase ENTPD5; MGC163357; MGC163359; mNTPase; NTPDase 5; Nucleoside diphosphatase; PCPH; Pcph proto oncogene protein; Proto oncogene CPH; UDPase ENTPD5; Uridine-diphosphatase ENTPD5 |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human ENTPD5/CD39L4 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Tumor biomarkers Epigenetics and Nuclear Signaling > DNA / RNA > DNA / Nucleotides Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Nucleotide metabolism Metabolism > Types of disease > Cancer Signal Transduction > Metabolism > Energy Metabolism |
| 亚细胞定位 | Endoplasmic reticulum membrane, Single-pass type II membrane protein |
| 组织特异性 | Expressed in adult liver, kidney, prostate, testis and colon. Much weaker expression in other tissues. |
| 翻译后修饰 | N-glycosylated; high-mannose type |
| 相似性 | Belongs to the GDA1/CD39 NTPase family. |
| 功能 | Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. Also hydrolyzes GDP and IDP but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The protein encoded by this gene is similar to E-type nucleotidases (NTPases)/ecto-ATPase/apyrases. NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD5 contains 4 apyrase-conserved regions which is characteristic of NTPases. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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CD39L4 Rabbit pAb, FITC conjugated(bs-6526R-FITC)-100ul
￥2980
