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- bsm-43036M-Bio
- 2025年09月30日
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100ul
| 产品编号 | bsm-43036M-Bio |
| 英文名称 | SIGLEC15 Mouse mAb, Biotin conjugated |
| 中文名称 | Biotin标记的唾液酸结合性免疫球蛋白样凝集素15单克隆抗体 |
| 英文别名 | CD33 antigen-like 3; CD33 molecule-like 3; CD33L3; HsT1361; Sialic acid-binding Ig-like lectin 15; SIG15_HUMAN; Siglec-15; SIGLEC15. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Mouse |
| 免疫原 | Recombinant human SIGLEC15 protein |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Monoclonal |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚细胞定位 | Membrane. |
| 组织特异性 | Expressed in macrophage and/or dendritic cells of spleen and lymph nodes. |
| 相似性 | Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family. _x000D_ Contains 1 Ig-like C2-type (immunoglobulin-like) domain._x000D_ Contains 1 Ig-like V-type (immunoglobulin-like) domain. |
| 功能 | Binds sialylated glycoproteins. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Two families of mammalian lectin-like adhesion molecules, the selectins and the sialoadhesins, bind glycoconjugate ligands in a sialic acid-dependent manner. The sialic acid-binding immunoglobulin superfamily lectins, designated Siglecs or sialoadhesins, recognize sialylated ligands and play a key role in mediating sialic-acid dependent binding to cells. Siglec-15 (sialic acid binding Ig-like lectin 15), also known as CD33L3, is a 328 amino acid single-pass type I membrane protein that contains one Ig-like C2-type domain and one Ig-like V-type domain. Expressed in dendritic and macrophage cells, Sinlec-15 interacts with DAP10 and DAP12 and binds to sialylated glycoproteins. The gene encoding Siglec-15 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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SIGLEC15 Mouse mAb, Biotin conjugated(bsm-43036M-Bio)-100ul
￥2980
