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- bs-10023R-Bio
- 2025年09月30日
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100ul
| 产品编号 | bs-10023R-Bio |
| 英文名称 | STAT4 Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的信号转导和转录激活因子4抗体 |
| 英文别名 | signal transducers and activators of transduction 4; CIS4; HSPC060; SOCS4; SOCS6; SSI4; STAI4; STAT 4; STAT4; STATI4; Suppressor of cytokine signaling 6; STAT4_HUMAN. |
| 产品应用 | WB=1000-10000, ICC/IF=1:50-200, ELISA=1:500-5000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human STAT4 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Signal transduction > Nuclear signaling > STAT family Epigenetics and Nuclear Signaling > Nuclear Signaling Pathways > STATs Epigenetics and Nuclear Signaling > Transcription > Other factors Kits/ Lysates/ Other > Kits > ELISA Kits > In Cell ELISA Kits > Phosphoprotein ICE kits Signal Transduction > Signaling Pathway > Nuclear Signaling > STATs |
| 亚基 | Forms a homodimer or a heterodimer with a related family member. Interacts with ARL2BP. The SH2 domain interacts, in vitro, with IL12RB2 via a short cytoplasmic domain. |
| 亚细胞定位 | Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation. |
| 翻译后修饰 | Tyrosine phosphorylated. Serine phosphorylation is also required for maximal transcriptional activity. |
| 相似性 | Belongs to the transcription factor STAT family. Contains 1 SH2 domain. |
| 功能 | Carries out a dual function: signal transduction and activation of transcription. Involved in IL12 signaling. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]. |
| 应用 | 推荐稀释比例 |
| {WB} | {1000-10000} |
| {ICC/IF} | {1:50-200} |
| {ELISA} | {1:500-5000} |
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STAT4 Rabbit pAb, Biotin conjugated(bs-10023R-Bio)-100ul
￥2980
