FoxP1 Rabbit pAb, BF405 conjugated(bs-1275R-BF405)-100ul

FoxP1 Rabbit pAb, BF405 conjug

ated(bs-1275R-BF405)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-1275R-BF405
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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    • 规格

      100ul

    产品编号bs-1275R-BF405
    英文名称FoxP1 Rabbit pAb, BF405 conjugated
    中文名称BF405标记的叉头蛋白P1抗体
    英文别名FLJ23741; Fork head related protein like B; Forkhead box P1; Forkhead box protein P1; 12CC4; FOXP1_MOUSE; FOX P1; FOXP 1; Glutamine rich factor 1; hFKH1B; HSPC215; MGC12942; MGC88572; MGC99551; QRF 1; QRF1.
    产品应用ICC/IF=1:100-500, Flow-Cyt=1ug/test

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from mouse FoxP1
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Oncoproteins/suppressors > Tumor suppressors

    Epigenetics and Nuclear Signaling > Transcription > Domain Families > Forkhead Box

    Epigenetics and Nuclear Signaling > Transcription > Domain Families > Forkhead Box > FOXP

    亚基Forms homodimers and heterodimers with FOXP2 and FOXP4. Dimerization is required for DNA-binding. Interacts with CTBP1.
    亚细胞定位Nucleus.
    组织特异性Highest expression in the lung, brain, and spleen. Lower expression in heart, skeletal muscle, kidney, small intestine (isoform 3 not present) and liver.
    相似性Contains 1 C2H2-type zinc finger.
    Contains 1 fork-head DNA-binding domain.
    功能Transcriptional repressor. It plays an important role in the specification and differentiation of lung epithelium. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Essential transcriptional regulator of B cell development.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

     

    应用推荐稀释比例
    {ICC/IF}{1:100-500}
    {Flow-Cyt}{1ug/test}

     

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