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- bs-3754R-Bio
- 2025年09月30日
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100ul
| 产品编号 | bs-3754R-Bio |
| 英文名称 | Claudin 6 Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的紧密连接蛋白6抗体 |
| 英文别名 | Claudin6; CLDN 6; CLDN6; Skullin 2; CLD6_HUMAN; Claudin-6; Claudin 6; OTTHUMP00000159248; Skullin-2; Skullin; UNQ757/PRO1488. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Claudin 6 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Developmental Biology > Lineage specification > Endoderm Microbiology > Interspecies Interaction > Host Virus Interaction Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Tight Junctions Stem Cells > Lineage Markers > Endoderm |
| 亚基 | Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3. |
| 亚细胞定位 | Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. |
| 相似性 | Belongs to the claudin family. |
| 功能 | Plays a major role in tight junction-specific obliteration of the intercellular space. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.[provided by RefSeq, Aug 2010] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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Claudin 6 Rabbit pAb, Biotin conjugated(bs-3754R-Bio)-100ul
￥2980
