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- bs-13904R-HRP
- 2025年09月30日
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100ul
| 产品编号 | bs-13904R-HRP |
| 英文名称 | CHIT1 Rabbit pAb, HRP conjugated |
| 中文名称 | HRP标记的几丁质酶1抗体 |
| 英文别名 | CHI3; CHIT; CHIT1; CHIT1_HUMAN; CHITD; Chitinase 1; Chitinase 1(chitotriosidase); Chitinase-1; Chitotriosidase; Chitotriosidase-1; EC 3.2.1.14; FLJ00314; MGC125322; Plasma methylumbelliferyl tetra N acetylchitotetraoside hydrolase. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human CHIT1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Immunology > Innate Immunity > Macrophage / Inflamm. |
| 亚细胞定位 | Secreted. Lysosome. A small proportion is lysosomal. |
| 组织特异性 | Detected in spleen. Secreted by cultured macrophages. |
| 相似性 | Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily. _x000D_ Contains 1 chitin-binding type-2 domain. |
| 功能 | Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2012] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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CHIT1 Rabbit pAb, HRP conjugated(bs-13904R-HRP)-100ul
￥2980
