APOA1BP/AI-BP Rabbit pAb, Biotin conjugated(bs-12491R-Bio)-100ul

APOA1BP/AI-BP Rabbit pAb, Biot

in conjugated(bs-12491R-Bio)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-12491R-Bio
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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    • 规格

      100ul

    产品编号bs-12491R-Bio
    英文名称APOA1BP/AI-BP Rabbit pAb, Biotin conjugated
    中文名称Biotin标记的载脂蛋白A1结合蛋白抗体抗体
    英文别名AI BP; AIBP; ApoA I binding protein; Apolipoprotein A I binding protein; MGC119143; MGC119144; MGC119145; YjeF N terminal domain containing protein 1; YJEFN1; NNRE_HUMAN.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human APOA1BP/AI-BP
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cardiovascular > Lipids / Lipoproteins > Lipoproteins/Apolipoproteins > Apolipoproteins

    亚基Homodimer (By similarity). Interacts with APOA1 and APOA2.
    亚细胞定位Secreted
    组织特异性Ubiquitously expressed, with highest levels in kidney, heart and liver. Present in cerebrospinal fluid and urine but not in serum from healthy patients. Present in serum of sepsis patients (at protein level).
    翻译后修饰Undergoes physiological phosphorylation during sperm capacitation, downstream to PKA activation (By similarity).
    相似性Belongs to the nnrE/AIBP family.
    Contains 1 YjeF N-terminal domain.
    功能APOA1BP interacts with apolipoprotein A-I (apoA-I), the major apolipoprotein of high-density lipoproteins (HDLs). It is secreted into some bodily fluids, and its synthesis and secretion are stimulated in vitro by incubating cells with apoA-I.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料Apolipoproteins are protein components of plasma lipoproteins. Apolipoprotein A-I (ApoA1) promotes cholesterol efflux from tissues to the liver for excretion. ApoA1 is the major protein component of high density lipoprotein (HDL) in the plasma. It can function as a cofactor for lecithin cholesterolacyltransferase, which is responsible for the formation of most plasma cholesteryl esters. AI-BP (Apolipoprotein A-I-binding protein), also known as YjeF N-terminal domain-containing protein 1, is a 288 amino acid secreted protein that binds ApoA1, ApoA2 and HDL. Individuals with impaired renal function show an increased rate of AI-BP excretion, indicating that it is normally reabsorbed within the kidney tubules. AI-BP belongs to the YjeF N-terminal domain protein family, which includes proteins that are frequently involved in oogenesis and spermatogenesis. There are two isoforms of AI-BP that are produced as a result of alternative splicing events.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

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