HOXA3 Rabbit pAb, BF594 conjugated(bs-11292R-BF594)-100ul

HOXA3 Rabbit pAb, BF594 conjug

ated(bs-11292R-BF594)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-11292R-BF594
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-11292R-BF594
    英文名称HOXA3 Rabbit pAb, BF594 conjugated
    中文名称BF594标记的同源盒基因HOXA3蛋白抗体
    英文别名Homeo box 1E; Homeo box A3; Homeobox 1E; Homeobox A3; Homeobox protein HOX A3; Homeobox protein Hox-1E; Homeobox protein Hox-A3; Homeobox protein HOXA3; Homeobox1E; HomeoboxA3; HOX 1; Hox 1.5 like protein; HOX 1E; HOX A3; HOX1; Hox1.5; Hox1.5 like protein; HOX1E; HOXA 3; HOXA3; HXA3_HUMAN; MGC10155.
    产品应用ICC/IF=1:50-200, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human HOXA3
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families > HOX

    亚细胞定位Nucleus.
    相似性Belongs to the Antp homeobox family.
    _x000D_ Contains 1 homeobox DNA-binding domain.
    功能Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料The Hox proteins play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. The mammalian HOX gene complex consists of 39 genes that are located on four linkage groups, which are dispersed over four chromosomes. HOX genes that occupy the same relative position along the 5’ to 3’ coordinate (trans-paralogous genes) are more similar in sequence and expression pattern than adjacent HOX genes on the same chromosome. HoxA3, in conjunction with Pax1, mediates the development of the thymus, parathyroid gland, and carotid body. Its expression in the third pharyngeal arch and pouch is required for development of the third arch artery, and homozygous null HoxA3 mutants lack the carotid body. HoxA3 also regulates hindbrain development by controlling the axon projection pattern of motor neurons and sensory neurons of the proximal and distal ganglia.

     

    应用推荐稀释比例
    {ICC/IF}{1:50-200}
    {IF}{1:100-500}

     

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