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- bs-11213R-Bio
- 2025年09月30日
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100ul
| 产品编号 | bs-11213R-Bio |
| 英文名称 | LRRTM1 Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的富含亮氨酸重复跨膜神经元蛋白1抗体 |
| 英文别名 | Leucine rich repeat transmembrane neuronal 1; Leucine rich repeat transmembrane neuronal 1 protein; Leucine-rich repeat transmembrane neuronal protein 1; LRRT1_HUMAN; LRRTM1; Lrrtm1 leucine rich repeat transmembrane neuronal 1; OTTHUMP00000194829; 4632401D06Rik; AW125451; FLJ32082. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human LRRTM1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Developmental Biology > Organogenesis > Nervous system development Neuroscience > Cell Type Marker > Neuron marker > Axon marker Neuroscience > Cell Type Marker > Neuron marker > Growth Cone Neuroscience > Neurology process > Neurogenesis |
| 亚细胞定位 | Cell membrane; Single-pass type I membrane protein (By similarity). Cell junction, synapse, postsynaptic cell membrane; Single-pass type I membrane protein (By similarity). |
| 组织特异性 | Predominantly expression in forebrain regions including thalamus and cerebral cortex. |
| 相似性 | Belongs to the LRRTM family. Contains 10 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 LRRNT domain. |
| 功能 | May play a role during the development of specific forebrain structures by influencing neuronal differentiation and connectivity, with a possible role in intracellular trafficking within axons. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic Alpha/Beta horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. LRRTM1 (leucine rich repeat transmembrane neuronal 1) is a 522 amino acid single-pass type I membrane protein that localizes to the endoplasmic reticulum and contains ten LRR repeats. Expressed predominately in forebrain tissue, LRRTM1 is thought to be involved in the development of forebrain structures, specifically by influencing axon trafficking, as well as neuronal differentiation and connectivity. Human LRRTM1 shares 96% amino acid identity with its mouse counterpart, suggesting a conserved role between species. Defects in the gene encoding LRRTM1 may be associated with the pathogenesis of several common neurodevelopmental disorders. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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LRRTM1 Rabbit pAb, Biotin conjugated(bs-11213R-Bio)-100ul
￥2980
