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- bs-8523R-Cy3
- 2025年09月30日
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100ul
| 产品编号 | bs-8523R-Cy3 |
| 英文名称 | TET1 Rabbit pAb, Cy3 conjugated |
| 中文名称 | Cy3标记的Ten-eleven转运基因1蛋白抗体 |
| 英文别名 | Leukemia associated protein with a CXXC domain; CXXC 6; CXXC finger 6; CXXC type zinc finger protein 6; CXXC-type zinc finger protein 6; CXXC6; KIAA1676; LCX; Leukemia-associated protein with a CXXC domain; Methylcytosine dioxygenase TET1; Ten eleven translocation 1 gene protein; Ten eleven translocation 1 gene protein homolog; Ten-eleven translocation 1 gene protein; Tet 1; Tet oncogene 1; TET1; TET1_HUMAN; TET1/CXXC6. |
| 产品应用 | ICC/IF=1:100-500, IF=1:100-500, Flow-Cyt=1ug/test Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human TET1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Oncoproteins/suppressors > Oncoproteins > Transcription factors Epigenetics and Nuclear Signaling > DNA methylation > Methylated DNA Associated Epigenetics and Nuclear Signaling > Transcription > Cancer susceptibility > Proto-oncogenes |
| 亚基 | Interacts with SIN3A; recruits the transcriptional co-repressor SIN3A to gene promoters. |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Expressed in fetal heart, lung and brain, and in adult skeletal muscle, thymus and ovary. |
| 相似性 | Belongs to the TET family._x000D_
Contains 1 CXXC-type zinc finger. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | TET1 (tet oncogene 1), also known as LCX or CXXC6, is a 2,136 amino acid protein that localizes to the nucleus and contains one CXXC-type zinc finger. Expressed in adult ovary, thymus and skeletal muscle and also present in fetal lung, heart and brain, TET1 is thought to play a role in the development of fetal organs and may also be involvement in the pathoegenesis and metastasis of acute myeloid leukemia (AML). The gene encoding TET1 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria. |
| 应用 | 推荐稀释比例 |
| {ICC/IF} | {1:100-500} |
| {IF} | {1:100-500} |
| {Flow-Cyt} | {1ug/test} |
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TET1 Rabbit pAb, Cy3 conjugated(bs-8523R-Cy3)-100ul
￥2980
