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100ul
| 产品编号 | bs-20807R-APC-Cy7 |
| 英文名称 | CLCA4 Rabbit pAb, APC-Cy7 conjugated |
| 中文名称 | APC-Cy7标记的钙激活氯通道调节蛋白4抗体 |
| 英文别名 | Cl30 kDa form; CaCC-2; Calcium-activated chloride channel family member 4; Calcium-activated chloride channel protein 2; Calcium-activated chloride channel regulator 4; Clca4; CLCA4_HUMAN; hCaCC-2; CLCA4 chloride channel accessory 4; hCLCA4. |
| 产品应用 | Flow-Cyt=2ug/Test Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human CLCA4 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Metabolism > Plasma Membrane > Channels |
| 亚细胞定位 | Cell membrane; Single-pass membrane protein. Apical cell membrane. Secreted. Note=The C-terminus 30 kDa form is anchored to the membrane. The N-terminus 110 kDa form is released from the membrane triggered by an unknown stimulus. Associated with the microvilli of non-goblet cell enterocytes in the small and large intestine. Co-localizes with CFTR. |
| 组织特异性 | Primarily expressed in the digestive tract, mainly in colon. Detected in smaller amounts in brain, urogenital organs, testis, and salivary and mammary glands. Highly expressed in the epithelial layer and submucosal gland of the inferior turbinate mucosa. Lower levels in the epithelial layer of nasal polyp. |
| 翻译后修饰 | N-Glycosylated._x000D_
Processed at a monobasic residue to yield a larger N-terminal and a smaller C-terminal cleavage products of 90 to 110 and 30 to 35 kDa, respectively. |
| 相似性 | Belongs to the CLCR family._x000D_
Contains 1 VWFA domain. |
| 功能 | May be involved in mediating calcium-activated chloride conductance. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Alternative splicing results in multiple transcript variants, only one of which is thought to be protein coding. [provided by RefSeq, Dec 2008] |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {2ug/Test} |
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CLCA4 Rabbit pAb, APC-Cy7 conjugated(bs-20807R-APC-Cy7)-100ul
¥2980





