CD11a Rabbit pAb, AP conjugated(bs-42274R-AP)-100ul

CD11a Rabbit pAb, AP conjugate

d(bs-42274R-AP)-100ul
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  • ￥2980
  • Bioss已认证
  • bs-42274R-AP
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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北京博奥森生物技术有限公司
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      产品信息以Bioss网站为准

    • 规格：

      100ul

    产品编号bs-42274R-AP
    英文名称CD11a Rabbit pAb, AP conjugated
    中文名称AP标记的整合素αL抗体
    英文别名Integrin alpha L; Integrin alpha-L; Leukocyte adhesion glycoprotein LFA-1 alpha chain; LFA-1A; Leukocyte function-associated molecule 1 alpha chain; Lymphocyte antigen 15; Ly-15; CD11 antigen-like family member A; CD_antigen; ITAL_HUMAN.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原Recombinant human CD11a protein
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Immunology > Cell Type Markers > CD > Adhesion

    Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Integrins > Alpha

    Stem Cells > Hematopoietic Progenitors > Lymphoid > NK Cell Lineage

    Stem Cells > Hematopoietic Progenitors > Lymphoid > T Lymphocytic Lineage

    Stem Cells > Hematopoietic Progenitors > Myeloid > Erythrocytic Lineage

    Stem Cells > Hematopoietic Progenitors > Myeloid > Mast Cell Lineage

    Stem Cells > Hematopoietic Progenitors > Myeloid > Monocytic Lineage

    Stem Cells > Hematopoietic Progenitors > Myeloid > Neutrophil Lineage

    亚基Heterodimer of an alpha and a beta subunit. Alpha-L associates with beta-2.
    亚细胞定位Membrane; Single-pass type I membrane protein.
    组织特异性Leukocytes.
    相似性Belongs to the integrin alpha chain family.
    _x000D_ Contains 7 FG-GAP repeats.
    _x000D_ Contains 1 VWFA domain.
    功能Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    背景资料ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

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