TLR7 Recombinant Rabbit mAb, PE conjugated(bsm-41320R-PE)-100ul产品图

TLR7 Recombinant Rabbit mAb, P

E conjugated(bsm-41320R-PE)-100ul
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  • ¥3200
  • Bioss已认证
  • bsm-41320R-PE
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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    • 规格:

      100ul

    产品编号bsm-41320R-PE
    英文名称TLR7 Recombinant Rabbit mAb, PE conjugated
    中文名称PE标记的Toll样受体7重组兔单抗
    英文别名TLR-7; PRO285; TLR 7; TLR7_HUMAN; Toll like receptor 7; Toll-like receptor 7; UNQ248.
    产品应用Flow-Cyt=1ug/Test

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原Recombinant human TLR7 protein
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Recombinant
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families

    Immunology > Immunoglobulins > Receptors

    Immunology > Innate Immunity > Macrophage / Inflamm.

    Immunology > Innate Immunity > TLR Signaling

    Signal Transduction > Adapters > Transmembrane

    亚基Interacts with MYD88 via their respective TIR domains. Interacts with UNC93B1.
    亚细胞定位Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endosome. Lysosome. Cytoplasmic vesicle, phagosome. Note=Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist.
    组织特异性Detected in brain, placenta, spleen, stomach, small intestine, lung and in plasmacytoid pre-dendritic cells.
    相似性Belongs to the Toll-like receptor family.
    Contains 27 LRR (leucine-rich) repeats.
    Contains 1 TIR domain.
    功能Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

     

    应用推荐稀释比例
    {Flow-Cyt}{1ug/Test}

     

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