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产品信息以Bioss网站为准
- 规格:
100ul
| 产品编号 | bs-10985R-Cy7 |
| 英文名称 | MX2 Rabbit pAb, Cy7 conjugated |
| 中文名称 | Cy7标记的干扰素诱导GTP结合蛋白MX2抗体 |
| 英文别名 | Interferon induced GTP binding protein Mx2; Interferon regulated resistance GTP binding protein MXB; Interferon-induced GTP-binding protein Mx2; Interferon-regulated resistance GTP-binding protein MxB; MX 2; MX dynamin like GTPase 2; Mx2; MX2_HUMAN; MXB; Myxovirus(influenza virus) resistance 2; Myxovirus resistance 2; Myxovirus resistance protein 2; p78 related protein; p78-related protein; Second interferon induced protein p78. |
| 产品应用 | ICC/IF=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human MX2 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Immunology > Innate Immunity > Cytokines > Interferons |
| 亚基 | Interacts with TRPC1, TRPC3, TRPC4, TRPC5, TRPC6 and TRPC7. |
| 亚细胞定位 | Cytoplasm. |
| 相似性 | Belongs to the dynamin family. Contains 1 GED domain. |
| 功能 | May regulate the calcium channel activity of TRPCs. Shows activity against influenza virus and VSV, a rhabdovirus. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Members of the Dynamin family include GTPase, microtubule-associated proteins that are involved in cellular trafficking, including microtubule bundling and endocytosis. Mx1, also known as MxA, an interferon (IFN)-induced protein, acquires a high degree of resistance to influenza A virus and the rhabdo-virus vesicular stomatitis virus (VSV), which suggests that Mx1 plays an active role against influenza virus and the rhabdovirus VSV. Mx1 is a cytoplasmic protein that is 63% identical to the Mx2 protein, which lacks antiviral activity. Mx2 is also known as MxB and is localized at the cytoplasmic face of nuclear pores. Mx2 expression is not interferon-dependent and this protein is thought to regulate the efficiency and/or kinetics of nuclear import, a function which may have been usurped by its antiviral relatives. |
| 应用 | 推荐稀释比例 |
| {ICC/IF} | {1:100-500} |
| {IF} | {1:100-500} |
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MX2 Rabbit pAb, Cy7 conjugated(bs-10985R-Cy7)-100ul
¥2980





