NMUR1 Rabbit pAb, Cy7 conjugated(bs-11420R-Cy7)-100ul

NMUR1 Rabbit pAb, Cy7 conjugat

ed(bs-11420R-Cy7)-100ul
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  • ¥2980
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  • bs-11420R-Cy7
  • 2025年09月30日
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      100ul

    产品编号bs-11420R-Cy7
    英文名称NMUR1 Rabbit pAb, Cy7 conjugated
    中文名称Cy7标记的G蛋白偶联受体66/神经调节肽U受体1抗体
    英文别名FM-3; G protein-coupled receptor 66; G-protein coupled receptor 66; G-protein coupled receptor FM-3; GPR66; Growth hormone secretagogue receptor family Member 3; Neuromedin U Receptor 1; Neuromedin-U receptor 1; NMU-R1; NMUR1; NMUR1_HUMAN.
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human NMUR1
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Metabolism > Types of disease > Cancer

    Neuroscience > Endocrine system > Hypothalamic pituitary adrenal axis

    Neuroscience > Neurology process > Metabolism

    Neuroscience > Neurotransmission > Receptors / Channels > GPCR > More GPCR

    亚细胞定位Cell membrane; Multi-pass membrane protein.
    组织特异性Expressed in greatest abundance in peripheral organs, particularly in elements of the gastrointestinal and urogenital systems with highest levels in testes. In central nervous system structures express levels are much lower than those seen in peripheral organs. Within the CNS, has been detected in highest abundance in the cerebellum, dorsal root ganglia, hippocampus, and spinal cord.
    相似性Belongs to the G-protein coupled receptor 1 family.
    功能Receptor for the neuromedin-U and neuromedin-S neuropeptides.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料Neuromedin U is a neuropeptide with high activity on smooth muscle. It is widely expressed in gastrointestinal systems and central nervous system (CNS). Peripheral activities of neuromedin U include smooth muscle stimulation, ion transport alterations in the gut and the regulation of local blood flow and adrenocortical function. Neuromedin U receptors 1 and 2 (NMUR1 and NMUR2) are multi-pass membrane proteins that belong to the G-protein coupled receptor 1 family of proteins. Both NMUR1 and NMUR2 act as receptors for the neuromedin U neuropeptide. NMUR1 is detected in peripheral organs, particularly in urogenital and gastrointestinal systems, with highest levels in testis. It’s expression in CNS is low, but the protein has been detected in cerebellum, hippocampus, dorsal root ganglia and spinal cord. NMUR2 is predominantly detected in central nervous system with highest levels detected in medulla oblongata, spinal cord and thalamus. It may also be detected in testis but has low levels of expression in peripheral tissues.

     

     

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