LDL Rabbit pAb, BF647 conjugated(bs-2200R-BF647)-100ul

LDL Rabbit pAb, BF647 conjugat

ed(bs-2200R-BF647)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-2200R-BF647
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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    • 规格

      100ul

    产品编号bs-2200R-BF647
    英文名称LDL Rabbit pAb, BF647 conjugated
    中文名称BF647标记的低密度脂蛋白抗体
    英文别名apolipoprotein; low density; low density lipoprotein; Low density lipoprotein.
    产品应用Flow-Cyt=3ug/test, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原Lipoprotein, low density from human plasma
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cardiovascular > Atherosclerosis > Lipid transport

    Cardiovascular > Lipids / Lipoproteins > Lipoproteins/Apolipoproteins > Lipoproteins

    Metabolism > Types of disease > Heart disease

    Metabolism > Types of disease > Metabolic disorders

    Signal Transduction > Metabolism > Lipid metabolism

    亚细胞定位Secreted.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料LDL (low-density lipoprotein) is a type of lipoprotein that transports cholesterol and triglycerides from the liver to peripheral tissues. LDL enables fats and cholesterol to move within the water based solution of the blood stream. LDL also regulates cholesterol synthesis at these sites. The low density lipoprotein (LDL) receptor system coordinates the metabolism of cholesterol, an essential component of the plasma membrane of all mammalian cells. Study of this system has led to an enhanced understanding of the cellular basis of cholesterol homeostasis. It has also brought into focus an important mechanism of metabolic regulation--the process of receptor-mediated endocytosis (1). Data suggest that the juxtamembranous region of the cytoplasmic domain participates in protein:protein interactions that allow the low density lipoprotein receptor to cluster in coated pits (2). It has been shown that the family of LDL receptors may serve as viral receptors. Endocytosis of the Flaviviridae viruses, hepatitis C virus, GB virus C/hepatitis G virus, and bovine viral diarrheal virus (BVDV) was shown to be mediated by LDL receptors on cultured cells.

     

    应用推荐稀释比例
    {Flow-Cyt}{3ug/test}
    {IF}{1:100-500}

     

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