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- Bioss
- bs-42249R-HRP
- 2025年09月30日
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100ul
| 产品编号 | bs-42249R-HRP |
| 英文名称 | HLA E Rabbit pAb, HRP conjugated |
| 中文名称 | HRP标记的人类白细胞抗原E抗体 |
| 英文别名 | HLA class I histocompatibility antigen E alpha chain; DKFZp686P19218; EA1.2; EA2.1; HLA 6.2; HLA class I histocompatibility antigen alpha chain E; HLA class I histocompatibility antigen E alpha chain precursor; HLA-6.2; HLA6.2; HLAE; Lymphocyte antigen; Major histocompatibility complex class I E; MHC; MHC class I antigen E; MHC HLA E alpha 1; MHC HLA E alpha 2.1; HLA-E; QA1. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | Recombinant human HLA E protein |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚基 | Heterodimer of an alpha chain and a beta chain (beta-2-microglobulin). |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 相似性 | Belongs to the MHC class I family._x000D_
Contains 1 Ig-like C1-type (immunoglobulin-like) domain. |
| 功能 | Preferably binds to a peptide derived from the signal sequence of most HLA-A, -B, -C and -G molecules. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
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