PDK1/Mitochondrial Pyruvate dehydrogenase kinase 1 Rabbit pAb, BF350 conjugated(bs-3788R-BF350)-100ul

PDK1/Mitochondrial Pyruvate de

hydrogenase kinase 1 Rabbit pAb, BF350 conjugated(bs-3788R-BF350)-100ul
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  • ¥2980
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  • bs-3788R-BF350
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-3788R-BF350
    英文名称PDK1/Mitochondrial Pyruvate dehydrogenase kinase 1 Rabbit pAb, BF350 conjugated
    中文名称BF350标记的丙‌‌酮酸脱氢酶激酶1抗体
    英文别名PDHK1; mitochondrial; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1; HGNC:8809; Mitochondrial pyruvate dehydrogenase kinase isoenzyme 1; PDK 1; PDK-1; Pyruvate dehydrogenase kinase isoform 1; Pyruvate dehydrogenase kinase, isoenzyme 1; PDK1_HUMAN.
    产品应用Flow-Cyt=1ug/Test, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human PDK1
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Cancer Metabolism > Cellular metabolic process

    Cancer > Cancer Metabolism > Metabolic signaling pathway > Integration of energy metabolism

    Cancer > Cancer Metabolism > Metabolic signaling pathway > Metabolism of carbohydrates

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Carbohydrate metabolism

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Integration of energy

    Signal Transduction > Metabolism > Energy Metabolism

    亚细胞定位Mitochondrion matrix.
    组织特异性Expressed predominantly in the heart.
    相似性Belongs to the PDK/BCKDK protein kinase family._x000D_
    Contains 1 histidine kinase domain.
    功能Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    背景资料Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013]

     

    应用推荐稀释比例
    {Flow-Cyt}{1ug/Test}
    {IF}{1:100-500}

     

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