SEZ6L2 Rabbit pAb, PE conjugated(bs-21102R-PE)-100ul

SEZ6L2 Rabbit pAb, PE conjugat

ed(bs-21102R-PE)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-21102R-PE
  • 2025年10月15日
  • 产品信息以Bioss网站为准
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    • 规格

      100ul

    产品编号bs-21102R-PE
    英文名称SEZ6L2 Rabbit pAb, PE conjugated
    中文名称PE标记的癫痫相关蛋白6样蛋白2抗体
    英文别名FLJ90517; PSK 1; PSK; SE6L2_HUMAN; Seizure 6 like protein 2; Seizure 6-like protein 2; Seizure related 6 homolog(mouse) like 2; SEZ6L2; Type I transmembrane receptor(seizure related protein).
    产品应用ICC/IF=1:50-200, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human SEZ6L2
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚细胞定位Cell membrane. Endoplasmic reticulum membrane. Detected on cell surface of lung-cancer.
    翻译后修饰O-glycosylated with core 1 or possibly core 8 glycans.
    相似性Belongs to the SEZ6 family.
    Contains 3 CUB domains.
    Contains 5 Sushi (CCP/SCR) domains.
    功能Protein-lysine N-methyltransferase that specifically monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    背景资料This gene encodes a seizure-related protein that is localized on the cell surface. The gene is located in a region of chromosome 16p11.2 that is thought to contain candidate genes for autism spectrum disorders (ASD), though there is no evidence directly implicating this gene in ASD. Increased expression of this gene has been found in lung cancers, and the protein is therefore considered to be a novel prognostic marker for lung cancer. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]

     

    应用推荐稀释比例
    {ICC/IF}{1:50-200}
    {IF}{1:100-500}

     

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