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100ul
| 产品编号 | bs-41222R-HRP |
| 英文名称 | Lactoferrin Rabbit pAb, HRP conjugated |
| 中文名称 | HRP标记的乳铁蛋白抗体 |
| 英文别名 | CKRX; GIG12; Growth inhibiting protein 12; HLF2; Homo sapiens chemokine receptor X; Kaliocin 1; Lactoferrin; Lactoferroxin A; Lactoferroxin B; Lactoferroxin C; Lactoferroxin-C; Lactotransferrin; LF; LTF; Neutrophil lactoferrin; Talalactoferrin alfa; Talalactoferrin; TRFL_HUMAN. |
| 产品应用 | WB=1:1000-5000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | Purified native Human Lactoferrin protein |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cell Death > Apoptosis Cancer > Invasion/microenvironment > Apoptosis Cardiovascular > Blood > Serum Proteins |
| 亚基 | Monomer. Found in a complex with LTF, CLU, EPPIN and SEMG1. |
| 亚细胞定位 | Isoform 1: Secreted. Isoform DeltaLf: Cytoplasm. Nucleus. |
| 翻译后修饰 | Isoform DeltaLf: Ubiquitinated at Lys-379 and Lys-391. |
| 相似性 | Belongs to the transferrin family._x000D_
Contains 2 transferrin-like domains. |
| 功能 | Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate._x000D_
Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration._x000D_ Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while lactoferroxin B and C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors._x000D_ The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity._x000D_ Isoform DeltaLf: transcription factor with antiproliferative properties and inducing cell cycle arrest. Binds to DeltaLf response element found in the SKP1, BAX, DCPS, and SELH promoters.extracellular cation concentration. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration. Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while lactoferroxin B and C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:1000-5000} |
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Lactoferrin Rabbit pAb, HRP conjugated(bs-41222R-HRP)-100ul
¥2980





