Nucleoporin p62 Rabbit pAb, BF647 conjugated(bs-2935R-BF647)-100ul

Nucleoporin p62 Rabbit pAb, BF

647 conjugated(bs-2935R-BF647)-100ul
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  • ¥2980
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  • bs-2935R-BF647
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-2935R-BF647
    英文名称Nucleoporin p62 Rabbit pAb, BF647 conjugated
    中文名称BF647标记的核孔糖蛋白P62抗体
    英文别名NUP62_HUMAN; 62 kDa nucleoporin; DKFZp547L134; FLJ20822; FLJ43869; MGC841; Nuclear pore glycoprotein p62; nucleoporin 62kDa; nucleoporin p62; nucleoporin p62KD; NUP62; NUP62 protein; Nucleoporin Nup62; p62.
    产品应用Flow-Cyt=1ug/Test, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Nucleoporin p62
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Cell Death > Apoptosis > Nucleus

    Cell Biology > Apoptosis > Nucleus

    Epigenetics and Nuclear Signaling > Nuclear Signaling Pathways > Nuclear Receptors > Nuclear Pore Complex

    Signal Transduction > Growth Factors/Hormones > EGF

    Signal Transduction > Protein Trafficking > Nuclear Import / Export

    Signal Transduction > Signaling Pathway > Nuclear Signaling > NFkB Pathway

    Tags & Cell Markers > Subcellular Markers > Nucleus > Nuclear Pore

    亚基Component of the p62 complex, a complex at least composed of NUP62, NUP54, and NUPL1 (By similarity). Interacts with C11orf73/Hikeshi.
    亚细胞定位Nucleus, nuclear pore complex. Cytoplasm, cytoskeleton, spindle pole. Note=Central region of the nuclear pore, within the transporter. During mitotic cell division, it associates with the poles of the mitotic spindle.
    翻译后修饰O-glycosylated. Contains about 10 N-acetylglucosamine side chain sites predicted for the entire protein, amongst which only one in the C-terminal.
    相似性Belongs to the nucleoporin NSP1/NUP62 family.
    功能Essential component of the nuclear pore complex. The N-terminal is probably involved in nucleocytoplasmic transport. The C-terminal is probably involved in protein-protein interaction via coiled-coil formation and may function in anchorage of p62 to the pore complex.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug. This protein associates with the importin alpha/beta complex which is involved in the import of proteins containing nuclear localization signals. Multiple transcript variants of this gene encode a single protein isoform. [provided by RefSeq].

     

    应用推荐稀释比例
    {Flow-Cyt}{1ug/Test}
    {IF}{1:100-500}

     

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