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- Bioss
- bs-1390R-BF647
- 2025年09月30日
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100ul
| 产品编号 | bs-1390R-BF647 |
| 英文名称 | Cdc6 Rabbit pAb, BF647 conjugated |
| 中文名称 | BF647标记的细胞分裂周期蛋白6抗体 |
| 英文别名 | Cell Division Cycle protein 6; Cdc 18L; Cdc 6; CDC18(cell division cycle 18, S.pombe, homolog) like; CDC18(S.pombe); CDC18 like; CDC18(S.pombe); Cdc18L; CDC6 related protein; Cdc6p; Cell cycle controller; Cell division control protein 6; Cell division control protein 6 homolog; Cell division cycle 18; Cell division cycle 18 homolog; Cell division cycle 6 homolog; Cell division cycle 6 protein; HsCDC 18; HsCDC 6; HsCDC18; HsCDC6; p62; p62(cdc 6); p62(cdc6). |
| 产品应用 | Flow-Cyt=1ug/Test, IF=1:100-500, ICC/IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Cdc6 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cell Biology > Cell Cycle > Cell Division > Other cell division antibodies Epigenetics and Nuclear Signaling > DNA / RNA > DNA Synthesis |
| 亚基 | Interacts with PCNA, ORC1L, cyclin-CDK and HUWE1. |
| 亚细胞定位 | Nucleus. Cytoplasm. The protein is nuclear in G1 and cytoplasmic in S-phase cells. |
| 相似性 | Sequence similaritiesBelongs to the CDC6/cdc18 family._x000D_ |
| 功能 | Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Cell cycle events are regulated by the sequential activation and deactivation of cyclin depended kinase (Cdks) and by the proteolysis of cyclins. The cell division cycle (Cdc) genes are required at various points in the cell cycle. Cdc6 is the human homolog of Saccharomyces cerevisiae Cdc6, which is involved in the initiation of DNA replication. Cdc6 is essential for assembling the pre-replicative complex that forms at origins of DNA replication in the G1 phase of the cell cycle in budding yeast (S. cerevisiae). Cdc6 is also involved in checkpoint controls that ensure that DNA replication is completed before initiation of mitosis. |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {1ug/Test} |
| {IF} | {1:100-500} |
| {ICC/IF} | {1:100-500} |
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Cdc6 Rabbit pAb, BF647 conjugated(bs-1390R-BF647)-100ul
￥2980
