- ￥2980
- Bioss
- bs-2711R-Bio
- 2025年09月30日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
Claudin 8 Rabbit pAb, Biotin conjugated(bs-5016R-Bio)-100ul
￥2980
TET1 Rabbit pAb, PerCP-Cy7 conjugated(bs-8523R-PerCP-Cy7)-100ul
￥2980
NIS Rabbit pAb, HRP conjugated(bs-0448R-HRP)-100ul
￥2980PBOV1 Rabbit pAb, Cy5.5 conjugated(bs-5939R-Cy5.5)-100ul
￥2980
Integrin alpha 2 Rabbit pAb, Cy5.5 conjugated(bs-2635R-Cy5.5)-100ul
￥2980
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
100ul
| 产品编号 | bs-2711R-Bio |
| 英文名称 | IL27R Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的白细胞介素27受体抗体 |
| 英文别名 | Interleukin-27 receptor subunit alpha; IL27RA; IL-27R; IL27R alpha; IL-27R-alpha; IL-27RA; Interleukin 27 receptor alpha chain precursor; Protein CRL1; Type 1 T cell cytokine receptor; WSX1; Interleukin-27 Receptor, T Cell Cytokine Receptor; CRL1; zcytor1WSX-1; IL-27 receptor subunit alpha; IL-27R subunit alpha; Cytokine receptor-like 1; Type I T-cell cytokine receptor; TCCR; WSX-1; ZcytoR1; I27RA_HUMAN. |
| 中文别名 | Interleukin-27 receptor subunit alpha |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human IL27RA |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > Nuclear Signaling Pathways > STATs Immunology > Innate Immunity > Cytokines > Interleukins Signal Transduction > Signaling Pathway > Nuclear Signaling > STATs |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 组织特异性 | Highly expressed in lymphoid tissues such as spleen, lymph nodes and peripheral blood leukocytes. Weakly expressed in other tissues examined including heart, brain, fetal and adult lung, liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary, small intestine, kidney and colon. In the lymphoid system, higher level expression in CD4+ T-cell subsets than in CD8+ T-cell subsets. Also weaker expression in CD19+ B-cells and monocytes. |
| 相似性 | Belongs to the type I cytokine receptor family. Type 2 subfamily. Contains 3 fibronectin type-III domains. |
| 功能 | Receptor for IL27. Requires IL6ST/gp130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Involved in the regulation of Th1-type immune responses. Also appears to be involved in innate defense mechanisms. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Upon antigen challenge, T-helper cells differentiate into two functionally distinct subsets, Th1 and Th2. Th1 cells produce IL-2, IFN-gamma and lymphotoxin-b that augment the cell-mediated immune response, while Th2 cells secrete IL-4, IL-5, and IL-10 that enhance humoral immunity. The function of T-helper cells is regulated by cytokines. A novel cytokine receptor was recently identified and cloned. It is a new member in the type I cytokine receptor family and designated TCCR for T-cell cytokine receptor and WSX-1. TCCR deficient mice had impaired Th1 responses to protein antigen challenge, including decreased levels of IFN-gamma and Th1-dependent antibody IgG2a. TCCR is predominantly expressed in thymus, spleen, lymph nodes and peripheral blood leukocytes. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
IL27R Rabbit pAb, Biotin conjugated(bs-2711R-Bio)-100ul
￥2980
