- ￥2980
- Bioss
- bs-2253R-AP
- 2025年09月30日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
RUNX2 Rabbit pAb, BF594 conjugated(bs-1134R-BF594)-100ul
￥2980
hnRNP U Rabbit pAb, APC conjugated(bs-9092R-APC)-100ul
￥2980
HMGB1 Rabbit pAb, BF350 conjugated(bs-20633R-BF350)-100ul
￥2980HSL/LIPE Rabbit pAb, BF594 conjugated(bs-22905R-BF594)-100ul
￥2980
NVL Rabbit pAb, BF647 conjugated(bs-19551R-BF647)-100ul
￥2980
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
100ul
| 产品编号 | bs-2253R-AP |
| 英文名称 | CPSF4 Rabbit pAb, AP conjugated |
| 中文名称 | AP标记的剪切和多聚腺苷酸化特异性因子4抗体 |
| 英文别名 | Cleavage and polyadenylation specificity factor 30 kDa subunit; CPSF 30 kDa subunit; CPSF30; CPSF4; NAR; NEB1; No arches homolog; NS1 effector domain binding protein 1; CPSF4_RAT. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human CPSF4/CPSF30 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > DNA / RNA > RNA Processing Epigenetics and Nuclear Signaling > Transcription > Domain Families > Zinc Finger Microbiology > Interspecies Interaction > Host Virus Interaction |
| 亚基 | Component of the cleavage and polyadenylation specificity factor (CPSF) complex, composed of CPSF1, CPSF2, CPSF3, CPSF4 and FIP1L1. Interacts with FIP1L1. |
| 亚细胞定位 | Nucleus. |
| 相似性 | Belongs to the CPSF4/YTH1 family._x000D_
Contains 5 C3H1-type zinc fingers._x000D_ Contains 1 CCHC-type zinc finger. |
| 功能 | Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U). |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain. The NS1 effector domain functionally interacts with the cellular 30 kDa subunit of cleavage and polyadenylation specific factor 4, an essential component of the 3' end processing machinery of cellular pre-mRNAs. In influenza virus-infected cells, the NS1 protein is physically associated with cleavage and polyadenylation specific factor 4, 30kD subunit. Binding of the NS1 protein to the 30 kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end cleavage and polyadenylation of host pre-mRNAs. Thus the NS1 protein selectively inhibits the nuclear export of cellular, and not viral, mRNAs. Multiple alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
CPSF4 Rabbit pAb, AP conjugated(bs-2253R-AP)-100ul
￥2980
