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- Bioss
- bs-6284R-Bio
- 2025年09月30日
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100ul
| 产品编号 | bs-6284R-Bio |
| 英文名称 | TKTL1 Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的酮基移换酶样蛋白1抗体 |
| 英文别名 | TK 2; TK2; TKR; TKT 2; TKT2; TKTL1; TKTL1_HUMAN; Transketolase 2; Transketolase like 1; Transketolase like protein 1; Transketolase related protein; Transketolase-like protein 1; Transketolase-related protein; Transketolase2. |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human TKTL1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Tumor biomarkers > Enzymes Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism Signal Transduction > Metabolism > Energy Metabolism |
| 亚基 | Homodimer |
| 亚细胞定位 | Cytoplasm. Nucleus. Note=Predominantly cytoplasmic and to a lesser extent also nuclear. |
| 组织特异性 | Expressed in fetal and adult heart, brain, lung, liver, and kidney, and in adult placenta, skeletal muscle and pancreas. Up-regulated in various epithelial tumors. |
| 相似性 | Belongs to the transketolase family. |
| 功能 | Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a transketolase that acts as a homodimer and catalyzes the conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate to D-ribose 5-phosphate and D-xylulose 5-phosphate. This reaction links the pentose phosphate pathway with the glycolytic pathway. Variations in this gene may be the cause of Wernicke-Korsakoff syndrome. Three transcript variants encoding different isoforms have been found for this gene. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
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TKTL1 Rabbit pAb, Biotin conjugated(bs-6284R-Bio)-100ul
￥2980
