LRRTM3 Rabbit pAb, PE conjugated(bs-11571R-PE)-100ul

LRRTM3 Rabbit pAb, PE conjugat

ed(bs-11571R-PE)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-11571R-PE
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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    • 规格

      100ul

    产品编号bs-11571R-PE
    英文名称LRRTM3 Rabbit pAb, PE conjugated
    中文名称PE标记的富含亮氨酸重复跨膜神经元蛋白3抗体
    英文别名Leucine rich repeat transmembrane neuronal protein 3; Leucine-rich repeat transmembrane neuronal protein 3; LRRT3_HUMAN; Lrrtm3; MGC131810; PRO1693; UNQ803.
    产品应用Flow-Cyt=1μg/Test

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human LRRTM3
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Neuroscience > Neurology process > Neural Signal Transduction

    Neuroscience > Neurology process > Neurodegenerative disease > Alzheimer's disease

    Neuroscience > Neurology process > Neurogenesis

    Neuroscience > Neurology process > Neuroregeneration > Neuroregeneration

    亚细胞定位Cell membrane; Single-pass type I membrane protein (By similarity). Cell junction, synapse, postsynaptic cell membrane; Single-pass type I membrane protein
    组织特异性Expressed in neuronal tissues.
    相似性Belongs to the LRRTM family.
    _x000D_ Contains 10 LRR (leucine-rich) repeats.
    _x000D_ Contains 1 LRRCT domain.
    _x000D_ Contains 1 LRRNT domain.
    功能May play a role in the development and maintenance of the vertebrate nervous system.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic Alpha/Beta horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The LRRTM protein family plays a role in the regulation of various cellular events during nervous system development. Localizing predominantly to the nervous system, LRRTM family members are known to exhibit synaptogenic activity. LRRTM3 (leucine rich repeat transmembrane neuronal 3) is a 581 amino acid single-pass type I membrane protein belonging to the LRRTM family. LRRTM3 is involved in the development and maintenance of the vertebrate nervous system, and contains ten LRR repeats. Expressed in neuronal tissues, LRRTM3 is encoded by a gene that maps to a region of chromosome 10 that has been linked to late-onset Alzheimer disease and elevated plasma Beta-Amyloid. As a result of alternative splicing events, two LRRTM3 isoforms exist.

     

    应用推荐稀释比例
    {Flow-Cyt}{1μg/Test}

     

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