LARP1 Rabbit pAb, AP conjugated(bs-17101R-AP)-100ul

LARP1 Rabbit pAb, AP conjugate

d(bs-17101R-AP)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-17101R-AP
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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    • 规格

      100ul

    产品编号bs-17101R-AP
    英文名称LARP1 Rabbit pAb, AP conjugated
    中文名称AP标记的LARP1蛋白抗体
    英文别名1810024J12Rik; 3110040D16Rik; KIAA0731; La related protein; La ribonucleoprotein domain family, member 1; LARP; MGC19556; mKIAA0731; rCG_32791; RGD1306683; RP23-293I3.7.
    产品应用WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human LARP1
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Epigenetics and Nuclear Signaling > Chromatin Binding Proteins > DNA / RNA binding

    亚基Interacts with PABPC1/PABP. Associates with the mTORC1 complex. Interacts with EIF4E. _x000D_
    亚细胞定位 Cytoplasm
    相似性Belongs to the LARP family.
    _x000D_ Contains 1 HTH La-type RNA-binding domain.
    功能LARP1 belongs to the LARP family and contains 1 HTH La-type RNA-binding domain.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料LARP1 is a 1,096 amino acid protein belonging to the LARP family. LARP1 contains two conserved regions, one that shares homology with La/SSB proteins and one that is conserved only across LARP family proteins. Within the La/SSB conserved region, LARP1 contains a HTH La-type RNA-binding domain, which may indicate a role in RNA stabalization and folding. Upon DNA damage, LARP1 is phosphorylated by ATR or ATM. LARP1 interacts with many signaling intermediate proteins, including 14-3-3. Widely expressed, LARP1 levels are highest in heart. LARP1 exists as three isoforms produced by alternative splicing.

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}

     

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