LRIG3 Rabbit pAb, HRP conjugated(bs-1846R-HRP)-100ul

LRIG3 Rabbit pAb, HRP conjugat

ed(bs-1846R-HRP)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-1846R-HRP
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-1846R-HRP
    英文名称LRIG3 Rabbit pAb, HRP conjugated
    中文名称HRP标记的LRIG3抗体
    英文别名leucine rich repeats and immunoglobulin-like domains 3; LIG3; LRIG1-3; LRIG3_HUMAN.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human LRIG3
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Tumor biomarkers > Tumor antigens

    Developmental Biology > Embryogenesis > Embryonic stem cells > Intracellular

    Neuroscience > Sensory System > Auditory system

    Stem Cells > Embryonic Stem Cells > Surface Molecules

    亚基Interacts with EGFR, ERBB2 and ERBB4 (in vitro) (By similarity).
    亚细胞定位Cell membrane; Single-pass type I membrane protein (By similarity). Cytoplasmic vesicle membrane; Single-pass type I membrane protein (By similarity). Note=Detected in cytoplasmic vesicles when coexpressed with ERBB4 (By similarity).
    组织特异性Widely expressed.
    相似性Contains 3 Ig-like C2-type (immunoglobulin-like) domains. Contains 15 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 LRRNT domain.
    功能May play a role in craniofacial and inner ear morphogenesis during embryonic development. May act within the otic vesicle epithelium to control formation of the lateral semicircular canal in the inner ear, possibly by restricting the expression of NTN1 (By similarity).
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料LRIG3 is predicted to be a 1117 amino acid single pass transmembrane protein with 15 leucine rich repeats and 3 Ig domains in the extracellular region, and a short, novel cytoplasmic tail with no known motifs. It is believed that LRIG3 influences lateral ear canal morphogenesis. Expression and sub-cellular localization of LRIG3 might be of importance in the pathogenesis and prognosis of astrocytic tumors.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

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