- ￥2980
- Bioss
- bsm-43073M-FITC
- 2025年09月30日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
RBP4 Mouse mAb, APC-Cy7 conjugated(bsm-43011M-APC-Cy7)-100ul
￥2980
HMGCS2 Rabbit pAb, FITC conjugated(bs-5070R-FITC)-100ul
￥2980GLUT3 Rabbit pAb, APC-Cy5.5 conjugated(bs-1207R-APC-Cy5.5)-100ul
￥2980
METTL19 Rabbit pAb, HRP conjugated(bs-18816R-HRP)-100ul
￥2980Histone H3(di methyl K27) Mouse mAb, PE-Cy7 conjugated(bsm-33107M-PE-Cy7)-100ul
￥2980
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
100ul
| 产品编号 | bsm-43073M-FITC |
| 英文名称 | PD-L1 Mouse mAb, FITC conjugated |
| 中文名称 | FITC标记的人程序性死亡配体1单克隆抗体 |
| 英文别名 | Programmed cell death 1 ligand 1; CD274; B7 H; B7 H1; B7 homolog 1; B7-H1; B7H; B7H1; CD 274; CD274 antigen; CD274 molecule; MGC142294; MGC142296; OTTHUMP00000021029; PD L1; PD1L1_HUMAN; PD1L1_Mouse; PDCD1 ligand 1; PDCD1L1; PDCD1LG1; PDL 1; PDL1; Programmed death ligand 1; RGD1566211. |
| 产品应用 | Flow-Cyt=1ug/Test Not yet tested in other applications. |
| 抗体来源 | Mouse |
| 免疫原 | Recombinant human PD-L1 protein |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Monoclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Tumor biomarkers > Tumor antigens Cancer > Tumor immunology > Tumor-associated antigens Immunology > Cell Type Markers > CD > Non-lineage Immunology > Immune System Diseases > Autoimmune Signal Transduction > Antibodies > pd-l1 |
| 亚基 | Interacts with PDCD1. |
| 亚细胞定位 | Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Endomembrane system; Single-pass type I membrane protein. |
| 组织特异性 | Highly expressed in the heart, skeletal muscle, placenta and lung. Weakly expressed in the thymus, spleen, kidney and liver. Expressed on activated T- and B-cells, dendritic cells, keratinocytes and monocytes. |
| 相似性 | Belongs to the immunoglobulin superfamily. BTN/MOG family. _x000D_ Contains 1 Ig-like C2-type (immunoglobulin-like) domain. _x000D_ Contains 1 Ig-like V-type (immunoglobulin-like) domain. |
| 功能 | Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {1ug/Test} |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
PD-L1 Mouse mAb, FITC conjugated(bsm-43073M-FITC)-100ul
￥2980
