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100ul
| 产品编号 | bs-0634R-FITC |
| 英文名称 | Aquaporin 4 Rabbit pAb, FITC conjugated |
| 中文名称 | FITC标记的水通道蛋白4抗体 |
| 英文别名 | aquaporin 4; WCH4; Mercurial-insensitive water channel; MIWC; AQP 4; AQP4; Aquaporin4; HMIWC 2; HMIWC2; Mercurial insensitive water channel; MGC22454; MIWC; AQP4_HUMAN; Aquaporin-4; AQP-4. |
| 产品应用 | Flow-Cyt=1μg /test, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human AQP4 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Metabolism > Plasma Membrane > Channels |
| 亚基 | Homotetramer. Part of a complex containing MLC1, TRPV4, HEPACAM and ATP1B1. |
| 亚细胞定位 | Membrane; Multi-pass membrane protein. |
| 组织特异性 | Brain, muscle, heart, kidney, lung, and trachea. |
| 相似性 | Belongs to the MIP/aquaporin (TC 1.A.8) family. |
| 功能 | Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. The encoded protein is the predominant aquaporin found in brain. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {1μg /test} |
| {IF} | {1:100-500} |
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文献和实验[IF={{ 4.362 }}] {Luis Alfonso González-Molina. et al. Extracellular Vesicles From 3xTg-AD Mouse and Alzheimer’s Disease Patient Astrocytes Impair Neuroglial and Vascular Components. Front Aging Neurosci. 2021; 13: 593927} {Other} {}
[IF={{ 4.362 }}] {Juan Villar-Vesga. et al. Differential Profile of Systemic Extracellular Vesicles From Sporadic and Familial Alzheimer’s Disease Leads to Neuroglial and Endothelial Cell Degeneration. Front Aging Neurosci. 2020; 12: 587989} {FCM} {Human}
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