- ￥2980
- Bioss
- bs-0057R-AP
- 2025年09月30日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
IGKV1-5 Rabbit pAb, PE conjugated(bs-18139R-PE)-100ul
￥2980C2orf72 Rabbit pAb, PerCP-Cy7 conjugated(bs-15159R-PerCP-Cy7)-100ul
￥2980
FLJ39378 Rabbit pAb, PE-Cy7 conjugated(bs-16137R-PE-Cy7)-100ul
￥2980
Ezrin/Radixin Rabbit pAb, Cy7 conjugated(bs-1343R-Cy7)-100ul
￥2980
EPB41 Rabbit pAb, PE-Cy5.5 conjugated(bs-13080R-PE-Cy5.5)-100ul
￥2980
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
100ul
| 产品编号 | bs-0057R-AP |
| 英文名称 | Amylin Rabbit pAb, AP conjugated |
| 中文名称 | AP标记的糖尿病相关肽/胰岛淀粉样肽抗体 |
| 英文别名 | Islet amyloid polypeptide; IAPP; DAP; Diabetes associated peptide; IAP; Insulinoma amyloid peptide. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Amylin |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cardiovascular > Atherosclerosis > Diabetes associated Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism Metabolism > Types of disease > Diabetes Metabolism > Types of disease > Heart disease Signal Transduction > Metabolism > Energy Metabolism |
| 亚基 | Interacts with IDE and INS. Can form homodimers. Interaction with INS inhibits homodimerization and fibril formation. |
| 亚细胞定位 | Secreted. |
| 翻译后修饰 | Amyloid fibrils are degraded by IDE. |
| 相似性 | Belongs to the calcitonin family. |
| 功能 | Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Amylin is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Recent results suggest that amylin, like the related beta amyloid (Abeta) assosciated with Alzheimer's disease, can induce apoptotic cell death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验SDS-PA gels, and subsequent detection of proteins using rabbit antisera and alkaline phosphatase-conjugated goat-anti-rabbit IgG, detected using bromo-chloro-indolyl phosphate (BCIP) and Nitro-blue tetrazolium (NBT) salts. ・
Developing Genetically Engineered Mouse Models to Study Tumor Suppression
Literature Cited Armstrong, J.F., Kaufman, M.H., Harrison, D.J., and Clarke, A.R. 1995. High‐frequency developmental abnormalities in p53‐deficient mice. Curr
技术资料暂无技术资料 索取技术资料
