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- bs-2217R-PerCP-Cy5.5
- 2025年09月30日
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100ul
| 产品编号 | bs-2217R-PerCP-Cy5.5 |
| 英文名称 | Integrin alpha E Rabbit pAb, PerCP-Cy5.5 conjugated |
| 中文名称 | PerCP-Cy5.5标记的整合素alpha E2（CD103）抗体 |
| 英文别名 | Itgae; A530055J10; alpha-E1; alpha-M290; aM290; CD103; MGC183601; antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide; ITAE_HUMAN; Integrin alpha-E; HML-1 antigen; Integrin alpha-IEL; Mucosal lymphocyte 1 antigen; Integrin alpha-E heavy chain; integrin alpha-E precursor. |
| 产品应用 | Flow-Cyt=1ug/test Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Integrin alpha-E heavy chain |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA and 0.02% Proclin300. |
| 研究领域 | Immunology > Adaptive Immunity > Regulatory T Cells Immunology > Cell Type Markers > CD > Adhesion Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Integrins > Alpha Stem Cells > Hematopoietic Progenitors > Lymphoid > T Lymphocytic Lineage |
| 亚基 | Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chains linked by a disulfide bond. Alpha-E associates with beta-7. |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 组织特异性 | Expressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells. |
| 相似性 | Belongs to the integrin alpha chain family._x000D_
Contains 7 FG-GAP repeats._x000D_ Contains 1 VWFA domain. |
| 功能 | Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. |
| 保存条件 | Store at 2-8°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {1ug/test} |
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Integrin alpha E Rabbit pAb, PerCP-Cy5.5 conjugated(bs-2217R-PerCP-Cy5.5)-100ul
￥2980
