ACTH (7-23) Rabbit pAb, HRP conjugated(bs-0004R-HRP)-100ul

ACTH (7-23) Rabbit pAb, HRP co

njugated(bs-0004R-HRP)-100ul
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  • ￥2980
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  • bs-0004R-HRP
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-0004R-HRP
    英文名称ACTH (7-23) Rabbit pAb, HRP conjugated
    中文名称HRP标记的促肾上腺皮质激素ACTH (7-23)抗体
    英文别名Adrenocorticotropic hormone; Adrenocorticotropin; Adrenocorticotropin Hormone; alpha Melanocyte Stimulating Hormone; beta Endorphin; beta Lipotropin; beta Melanocyte Stimulating Hormone; CLIP; Corticotropin; Corticotropin Like Intermediary Peptide; Corticotropin lipotropin precursor; Lipotropin beta; Lipotropin gamma; LPH; Melanotropin alpha; Met Enkephalin; MSH; N‌‌PP; POC; POMC; Pro opiomelanocortin; Proopiomelanocortin.
    产品应用WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human ACTH
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Cancer Metabolism > Metabolic signaling pathway > Hormone biosynthesis

    Metabolism > Pathways and Processes > Endocrine metabolism > Hormone biosynthesis

    Neuroscience > Endocrine system > Hypothalamic pituitary adrenal axis

    Neuroscience > Neurotransmitter > Neuropeptides > Hormones

    Signal Transduction > Growth Factors/Hormones > Hormones

    亚基Belongs to the POMC family.
    亚细胞定位Secreted.
    组织特异性ACTH and MSH are produced by the pituitary gland.
    翻译后修饰Specific enzymatic cleavages at paired basic residues yield the different active peptides._x000D_
    O-glycosylated; reducing sugar is probably N-acetylgalactosamine.
    相似性Belongs to the POMC family.
    功能ACTH stimulates the adrenal glands to release cortisol._x000D_
    MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes._x000D_
    Beta-endorphin and Met-enkephalin are endogenous opiates.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008].

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}

     

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