CCR9 Rabbit pAb, AP conjugated(bs-1788R-AP)-100ul

CCR9 Rabbit pAb, AP conjugated

(bs-1788R-AP)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-1788R-AP
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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    • 规格

      100ul

    产品编号bs-1788R-AP
    英文名称CCR9 Rabbit pAb, AP conjugated
    中文名称AP标记的细胞表面趋化因子受体9抗体
    英文别名CCR-9; C C chemokine receptor D6; C C chemokine receptor type 9; C C CKR 9; CC Chemokine receptor CCR10; CC CKR 9; CCBP2; CCCKR9; CCR 9; CCR9; CDw199; CDw199 antigen; Chemokine C C motif receptor 9; Chemokine CC Motif Receptor 9; Chemokine receptor CCR 9; Chemokine-binding protein D6; CMKBR9; G protein coupled receptor 28; GPR 28; GPR 9 6; GPR28; GPR96; CCR9_HUMA.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human CCR9
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Immunology > Innate Immunity > Chemokines > Beta Chemokine Rec. (CCR)

    亚细胞定位Cell membrane; Multi-pass membrane protein.
    组织特异性Highly expressed in the thymus and low in lymph nodes and spleen.
    相似性Belongs to the G-protein coupled receptor 1 family.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. Two alternatively spliced transcript variants have been described.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

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