NRF1 Rabbit pAb, BF405 conjugated(bs-1342R-BF405)-100ul

NRF1 Rabbit pAb, BF405 conjuga

ted(bs-1342R-BF405)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-1342R-BF405
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-1342R-BF405
    英文名称NRF1 Rabbit pAb, BF405 conjugated
    中文名称BF405标记的核呼吸因子-1抗体
    英文别名erythroid derived 2; like 1; Locus control region factor 1; Locus control region-factor 1; NF-E2-related factor 1; NF2L1_HUMAN; NFE2 related factor 1; NFE2-related factor 1; NFE2L1; NRF-1; NRF 1; Nuclear factor; Nuclear factor erythroid 2-related factor 1; Nuclear factor erythroid derived 2 like 1; TCF-11; TCF11; Transcription factor 11; Transcription factor HBZ17; Transcription factor LCR F1; Transcription factor LCR-F1.
    产品应用Flow-Cyt=1ug/Test, IF=1:100-500, ICC/IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human NRF1
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Epigenetics and Nuclear Signaling > ChIP assays > ChIP antibodies

    Epigenetics and Nuclear Signaling > Transcription > Other factors

    Epigenetics and Nuclear Signaling > Transcription > Polymerase associated factors > Pol II Transcription

    Epigenetics and Nuclear Signaling > Transcription > Transcription Factors

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Nucleotide metabolism > Molecular processes > Mitochondrial transcription

    Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial Biogenesis

    亚基Homodimer. Binds DNA as a dimer. Interacts with PPRC1.
    亚细胞定位Nucleus
    组织特异性Ubiquitously expressed with strongest expression in skeletal muscle.
    翻译后修饰Phosphorylation enhances DNA binding.
    相似性Belongs to the NRF1/Ewg family.
    功能Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1. [provided by RefSeq, May 2014]

     

    应用推荐稀释比例
    {Flow-Cyt}{1ug/Test}
    {IF}{1:100-500}
    {ICC/IF}{1:100-500}

     

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