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- Bioss
- bs-1550R-BF405
- 2025年09月30日
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100ul
| 产品编号 | bs-1550R-BF405 |
| 英文名称 | NCX1 Rabbit pAb, BF405 conjugated |
| 中文名称 | BF405标记的钠钙交换蛋白1抗体 |
| 英文别名 | Na+/Ca2+exchanger 1; CNC; DKFZp779F0871; MGC119581; FLJ37694; FLJ43417; Na+/Ca2+exchange protein 1; Na+/Ca2+exchanger; NCX 1; NCX; SLC8A1; SLC8A1 protein; Sodium Calcium Exchanger; Sodium/calcium exchanger 1; Solute carrier family 8 member 1; NAC1_HUMAN. |
| 产品应用 | Flow-Cyt=0.2ug/test, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human NCX1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cancer Metabolism > Response to hypoxia Cardiovascular > Heart > Contractility > Inotropics Metabolism > Pathways and Processes > Metabolism processes > Hypoxia Signal Transduction > Signaling Pathway > Calcium Signaling > Calcium Channels |
| 亚细胞定位 | Cell membrane. |
| 组织特异性 | Expressed in cardiac sarcolemma, brain, kidney, liver, pancreas, skeletal muscle, placenta and lung. |
| 相似性 | Belongs to the sodium/potassium/calcium exchanger family. SLC8 subfamily. Contains 2 Calx-beta domains. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma(plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.[supplied by OMIM]. |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {0.2ug/test} |
| {IF} | {1:100-500} |
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NCX1 Rabbit pAb, BF405 conjugated(bs-1550R-BF405)-100ul
￥2980
