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- Bioss
- bs-0571R-HRP
- 2025年09月30日
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100ul
| 产品编号 | bs-0571R-HRP |
| 英文名称 | CCNA2 Rabbit pAb, HRP conjugated |
| 中文名称 | HRP标记的周期素A2抗体 |
| 英文别名 | CCNA2_HUMAN; Cyclin-A2; Cyclin-A; CCN1; CCN1; CCNA; cyclin A2; |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human CCNA2 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cell cycle > Cyclins > Cyclin A family Cardiovascular > Lipids / Lipoproteins > Lipoproteins/Apolipoproteins > Apolipoproteins Cell Biology > Cell Cycle > Cyclins Cell Biology > Cell Cycle > Cyclins > Cyclin A Family Epigenetics and Nuclear Signaling > Cell cycle > Cyclins > Cyclin A Family |
| 亚基 | Interacts with the CDK1 and CDK2 protein kinases to form a serine/threonine kinase holoenzyme complex. The cyclin subunit imparts substrate specificity to the complex. When associated with CDK2 (but not with CDK1), interacts with SCAPER. |
| 亚细胞定位 | Nucleus. Cytoplasm. Note=Cytoplasmic when associated with SCAPER. |
| 翻译后修饰 | Polyubiquitinated via 'Lys-11'-linked ubiquitin by the anaphase-promoting complex (APC/C), leading to its degradation by the proteasome. Deubiquitinated and stabilized by USP37 enables entry into S phase. |
| 相似性 | Belongs to the cyclin family. Cyclin AB subfamily. |
| 功能 | Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene belongs to the highly conserved cyclin family, whose members function as regulators of the cell cycle. This protein binds and activates cyclin-dependent kinase 2 and thus promotes transition through G1/S and G2/M. [provided by RefSeq, Aug 2016] |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
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CCNA2 Rabbit pAb, HRP conjugated(bs-0571R-HRP)-100ul
￥2980
