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- bs-1099R-APC-Cy7
- 2025年09月30日
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100ul
| 产品编号 | bs-1099R-APC-Cy7 |
| 英文名称 | CAPN1 Rabbit pAb, APC-Cy7 conjugated |
| 中文名称 | APC-Cy7标记的钙蛋白酶1抗体 |
| 英文别名 | Calcium activated neutral proteinase 1; Calpain1; Calpain-1; Calpain 1; Calpain 1 catalytic subunit; Calpain large polypeptide L1; Calpain mu type; CANP 1; CANP; CANPL1; CAPN 1; Cell proliferation inducing gene 30 protein; Cell proliferation inducing protein 30; Micromolar calpain; muCANP; muCL; Ca2 activated neutral protease; Calcium activated neutral proteinase small subunit; Calcium dependent protease small subunit 1; Calcium-activated neutral proteinase 1; Calpain 1(mu/I) large subunit; Calpain 1 catalytic subunit; Calpain 1 large subunit; Calpain Large Polypeptide L1; Calpain Large Polypeptide L1; Calpain mu type; Calpain mu-type; Calpain regulatory subunit; Calpain small subunit 1; Calpain-1 catalytic subunit; Calpain-1 large subunit; Calpain1; CAN1_HUMAN. |
| 产品应用 | Flow-Cyt=3ug/Test, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from mouse Calpain 1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cell Biology > Proteolysis / Ubiquitin > Proteolytic enzymes > Cysteine protease > Calpains Signal Transduction > Signaling Pathway > Calcium Signaling > Calpain |
| 亚基 | Forms a heterodimer with a small (regulatory) subunit (CAPNS1). |
| 亚细胞定位 | Cytoplasm. Cell membrane. Translocates to the plasma membrane upon Ca(2+) binding. |
| 组织特异性 | Ubiquitous. |
| 翻译后修饰 | Undergoes calcium-induced successive autoproteolytic cleavages that generate a membrane-bound 78 kDa active form and an intracellular 75 kDa active form. Calpastatin reduces with high efficiency the transition from 78 kDa to 75 kDa calpain forms. |
| 相似性 | Belongs to the peptidase C2 family. Contains 1 calpain catalytic domain. Contains 4 EF-hand domains. |
| 功能 | Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2010] |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {3ug/Test} |
| {IF} | {1:100-500} |
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CAPN1 Rabbit pAb, APC-Cy7 conjugated(bs-1099R-APC-Cy7)-100ul
￥2980
