- ￥2980
- Bioss
- bs-22009R-Bio
- 2025年09月30日
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100ul
| 产品编号 | bs-22009R-Bio |
| 英文名称 | GPX3 Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的谷胱甘肽过氧化酶3 |
| 英文别名 | Extracellular glutathione peroxidase; Glutathione peroxidase 3(plasma); Glutathione peroxidase 3; GPX 3; GPx P; GPx-3; GPx-P; GPX3; GPX3_HUMAN; GPXP; GSHPx 3; GSHPx P; GSHPx-3; GSHPx-P; Plasma glutathione peroxidase 3; Plasma glutathione peroxidase. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human GPX3 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cancer Metabolism > Cellular metabolic process Cell Biology > Other Antibodies > Oxidative Stress Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers Metabolism > Pathways and Processes > Redox metabolism > Antioxidants Metabolism > Pathways and Processes > Redox metabolism > Oxidative stress Signal Transduction > Metabolism > Mitochondrial |
| 亚基 | Homotetramer. |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Secreted in plasma. |
| 翻译后修饰 | The N-terminus is blocked. |
| 相似性 | Belongs to the glutathione peroxidase family. |
| 功能 | Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Glutathione peroxidases(Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organichydroperoxides by glutathione. There are several isoforms which differ in their primary structure and localization. The classical cytosolic/mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, first of the GPxfamily to be discovered. GPx2, also known as gastrointestinal GPx(GI-GPx), is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract.Extracellular plasma GPx(pGPxor GPx3) is mainly expressed by the kidney from where it is released into the blood. Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, can reduce many hydroperoxides including hydroperoxides integrated in membranes, hydroperoxylipids in low density lipoprotein orthymine. All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis-specific secretory GPx(eGPxor GPx5)isoforms, possess selenocysteine at the active site. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
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GPX3 Rabbit pAb, Biotin conjugated(bs-22009R-Bio)-100ul
￥2980
