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- bs-11533R-AP
- 2025年09月30日
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100ul
| 产品编号 | bs-11533R-AP |
| 英文名称 | PCSK2/Proprotein Convertase 2 Rabbit pAb, AP conjugated |
| 中文名称 | AP标记的神经内分泌转化酶2抗体 |
| 英文别名 | KEX2 like endoprotease 2; KEX2-like endoprotease 2; NEC 2; NEC2; NEC2_HUMAN; Neuroendocrine convertase 2; PC2; PCSK2; Prohormone convertase 2; Proprotein convertase 2; Proprotein convertase subtilisin/kexin type 2; SPC2. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Proprotein Convertase 2 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cell Biology > Proteolysis / Ubiquitin > Proteolytic enzymes > Serine protease > Proprotein Convertases Signal Transduction > Growth Factors/Hormones > Hormones Signal Transduction > Growth Factors/Hormones > Insulin / Insulin-like |
| 亚细胞定位 | Cytoplasmic vesicle, secretory vesicle. Note=Localized in the secretion granules. |
| 相似性 | Belongs to the peptidase S8 family. Furin subfamily. |
| 功能 | Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the subtilisin-like proprotein convertase family. These enzymes process latent precursor proteins into their biologically active products. The encoded protein plays a critical role in hormone biosynthesis by processing a variety of prohormones including proinsulin, proopiomelanocortin and proluteinizing-hormone-releasing hormone. Single nucleotide polymorphisms in this gene may increase susceptibility to myocardial infarction and type 2 diabetes. This gene may also play a role in tumor development and progression. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
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PCSK2/Proprotein Convertase 2 Rabbit pAb, AP conjugated(bs-11533R-AP)-100ul
￥2980
