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- bs-11530R-PE-Cy5.5
- 2025年09月30日
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100ul
| 产品编号 | bs-11530R-PE-Cy5.5 |
| 英文名称 | LAR Rabbit pAb, PE-Cy5.5 conjugated |
| 中文名称 | PE-Cy5.5标记的受体蛋白酪氨酸磷酸酶F抗体 |
| 英文别名 | LAR; LAR protein; LARFN5C; PTPRF; LARS; LCA homolog; Leukocyte antigen related(LAR) PTP receptor; Leukocyte antigen related; Leukocyte antigen related PTP receptor; Leukocyte antigen related tyrosine phosphatase; Leukocyte common antigen related; Protein Tyrosine Phosphatase Receptor Type F; Protein tyrosine phosphatase receptor type F polypeptide; Ptprf; PTPRF protein; PTPRF_HUMAN; Receptor linked protein tyrosine phosphatase LAR; Receptor type tyrosine protein phosphatase F; Receptor type tyrosine protein phosphatase F precursor; Receptor-type tyrosine-protein phosphatase F. |
| 产品应用 | Flow-Cyt=1μg/Test Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human PTPRF |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚基 | Interacts with GRIP1. Interacts with PPFIA1, PPFIA2 and PPFIA3. Interacts with INSR. |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 相似性 | Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily. _x000D_ Contains 8 fibronectin type-III domains. _x000D_ Contains 3 Ig-like C2-type (immunoglobulin-like) domains. _x000D_ Contains 2 tyrosine-protein phosphatase domains. |
| 功能 | Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity. _x000D_
The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {1μg/Test} |
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LAR Rabbit pAb, PE-Cy5.5 conjugated(bs-11530R-PE-Cy5.5)-100ul
￥2980
