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- 应用范围:
产品信息以Bioss网站为准
- 规格:
100ul
| 产品编号 | bs-18814R-HRP |
| 英文名称 | METTL1 Rabbit pAb, HRP conjugated |
| 中文名称 | HRP标记的甲基化样蛋白1抗体 |
| 英文别名 | C12orf1; D1075 like gene product; FLJ95748; Methyltransferase like 1; Methyltransferase like protein 1; Methyltransferase-like protein 1; Mettl1; TRM8; TRMB_HUMAN; TRMT8; tRNA(guanine N(7) ) methyltransferase; tRNA(guanine(46)-N(7))-methyltransferase; tRNA(guanine-N(7)-)-methyltransferase; tRNA(m7G46) methyltransferase; tRNA(m7G46)-methyltransferase; YDL201w. |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human METTL1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > DNA / RNA > RNA Processing Epigenetics and Nuclear Signaling > DNA / RNA > Translation > tRNAs |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Ubiquitous. |
| 翻译后修饰 | Phosphorylation at Ser-27 inactivates its catalytic activity but does not affect the interaction with WDR4. |
| 相似性 | Belongs to the methyltransferase superfamily. TrmB family. |
| 功能 | Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation. Alternative splice variants encoding different protein isoforms have been described for this gene. A pseudogene has been identified on chromosome X. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
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METTL1 Rabbit pAb, HRP conjugated(bs-18814R-HRP)-100ul
¥2980





