- ￥2980
- Bioss
- bs-9383R-Bio
- 2025年09月30日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
LDLR Rabbit pAb, BF350 conjugated(bs-20714R-BF350)-100ul
￥2980
PRRSV-GP5 Rabbit pAb, Biotin conjugated(bs-4504R-Bio)-100ul
￥2980HMG4/HMGB3 Rabbit pAb, Biotin conjugated(bs-8809R-Bio)-100ul
￥2980
E2F2 Rabbit pAb, PE-Cy5.5 conjugated(bs-1001R-PE-Cy5.5)-100ul
￥2980
LIM kinase 2 Rabbit pAb, Biotin conjugated(bs-18255R-Bio)-100ul
￥2980
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
100ul
| 产品编号 | bs-9383R-Bio |
| 英文名称 | CNOT2 Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的细胞表面趋化因子受体4相关蛋白2抗体 |
| 英文别名 | CCR4 associated factor 2; CCR4 NOT transcription complex subunit 2; CCR4-associated factor 2; CCR4-NOT transcription complex subunit 2; CDC36; CNOT2; CNOT2_HUMAN; HSPC131; MSTP046; Negative regulator of transcription 2; NOT2(negative regulator of transcription 2 yeast) homolog; NOT2; NOT2H. |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human CNOT2 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Mediator Complex |
| 亚基 | Subunit of the CCR4-NOT core complex that contains CHAF1A, CHAF1B, CNOT1, CNOT2, CNOT3, CNOT4, CNOT6 and CNOT8. |
| 亚细胞定位 | Cytoplasm. Nucleus. |
| 组织特异性 | Ubiquitous. Highly expressed in brain, heart, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood leukocytes. |
| 相似性 | Belongs to the CNOT2/3/5 family. |
| 功能 | The CCR4-NOT complex functions as general transcription regulation complex. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | CNOT2 (CCR4-NOT transcription complex subunit 2) is a ubiquitous protein encoded by the human gene CNOT2. CNOT2 belongs to the CNOT2/3/5 family and is part of the CCR4-NOT complex. The CCR4-NOT complex is an evolutionarily conserved, multi-component complex known to be involved in transcription as well as mRNA degradation. Various subunits (e.g. CNOT1, CNOT2) are involved in influencing nuclear hormone receptor activities. The CCR4-NOT complex is also involved in the regulation of Histone H3 lysine 4 methylation through a ubiquitin-dependent pathway that likely involves the proteasome. Increased expression of the CNOT2 subunit acts to strongly repress transcription by RNA polymerase II. This repressive effect is mediated by a conserved NOT-Box, which is located at the C-terminus of CNOT2 proteins. Repression by the NOT-Box is sensitive to treatment with the histone deacetylase (HDAC) inhibitor trichostatin A. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
CNOT2 Rabbit pAb, Biotin conjugated(bs-9383R-Bio)-100ul
￥2980
