Alx1 Rabbit pAb, HRP conjugated(bs-20404R-HRP)-100ul

Alx1 Rabbit pAb, HRP conjugate

d(bs-20404R-HRP)-100ul
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  • ￥2980
  • Bioss已认证
  • bs-20404R-HRP
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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北京博奥森生物技术有限公司
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    • 规格：

      100ul

    产品编号bs-20404R-HRP
    英文名称Alx1 Rabbit pAb, HRP conjugated
    中文名称HRP标记的软骨蛋白1抗体
    英文别名ALX homeobox 1; ALX homeobox protein 1; ALX1; ALX1_HUMAN; CART 1; CART-1; CART1; Cartilage homeoprotein 1.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500, WB=1000-10000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Alx1
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Developmental Biology > Embryogenesis > Morphogens

    Developmental Biology > Organogenesis > Skeletal development > Bone

    Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families

    Stem Cells > Mesenchymal Stem Cells > Chondrogenesis

    亚基Interacts (via homeobox domain) with EP300.
    亚细胞定位Nucleus.
    组织特异性Cartilage and cervix tissue.
    翻译后修饰Acetylated at Lys-131 by EP300, leading to increased interaction with EP300 and enhances transcriptional activation activity.
    相似性Belongs to the paired homeobox family._x000D_
    Contains 1 homeobox DNA-binding domain.
    功能Transcriptional activator that acts at a palindromic recognition sequence to enhance the activity of the SV40 and TK promoters. Functions as a repressor with the prolactin promoter in vivo. May play a role in chondrocyte differentiation and may also influence cervix development.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The specific function of this gene has yet to be determined in humans; however, in rodents, it is necessary for survival of the forebrain mesenchyme and may also be involved in development of the cervix. Mutations in the mouse gene lead to neural tube defects such as acrania and meroanencephaly. [provided by RefSeq, Jul 2008].

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {WB}{1000-10000}

     

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