- ￥2980
- Bioss
- bs-1024R-BF405
- 2025年09月30日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
COMT Rabbit pAb, APC-Cy5.5 conjugated(bs-15507R-APC-Cy5.5)-100ul
￥2980phospho-Dishevelled 2 (Ser143) Rabbit pAb, AP conjugated(bs-13004R-AP)-100ul
￥2980
MRF/C11orf9 Rabbit pAb, BF488 conjugated(bs-11191R-BF488)-100ul
￥2980ITPR2 Rabbit pAb, APC conjugated(bs-4243R-APC)-100ul
￥2980
Ephrin B3 Rabbit pAb, BF750 conjugated(bs-7043R-BF750)-100ul
￥2980
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
100ul
| 产品编号 | bs-1024R-BF405 |
| 英文名称 | GDNF Rabbit pAb, BF405 conjugated |
| 中文名称 | BF405标记的胶质细胞源性神经营养因子抗体 |
| 英文别名 | glial cell line derived neurotrophic factor; Astrocyte derived trophic factor 1; Astrocyte derived trophic factor; ATF 1; ATF 2; ATF1; ATF2; Glial cell derived neurotrophic factor; Glial derived neurotrophic factor; HFB1 GDNF; GDNF_HUMAN; Atf; gdnf; Glial Cell Line Derived Neurotrophic Factor; Glial cell line-derived neurotrophic factor; Glial derived neurotrophic factor; hGDNF; HSCR3. |
| 产品应用 | IF=1:200-800 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human GDNF |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Developmental Biology > Organogenesis > Excretory system development > Kidney development Neuroscience > Neurology process > Growth and Development > Neurotrophins Neuroscience > Neurology process > Neurodegenerative disease > Amyotrophic lateral sclerosis Neuroscience > Neurology process > Neurodegenerative disease > Parkinson's disease |
| 亚基 | Homodimer; disulfide-linked. |
| 亚细胞定位 | Secreted. |
| 组织特异性 | In the brain, predominantly expressed in the striatum with highest levels in the caudate and lowest in the putamen. Isoform 2 is absent from most tissues except for low levels in intestine and kidney. Highest expression of isoform 3 is found in pancreatic islets. Isoform 5 is expressed at very low levels in putamen, nucleus accumbens, prefrontal cortex, amygdala, hypothalamus and intestine. Isoform 3 is up-regulated in the middle temporal gyrus of Alzheimer disease patients while isoform 2 shows no change. |
| 相似性 | Belongs to the TGF-beta family. GDNF subfamily. |
| 功能 | Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Neurobiology. Neurotrophins. Neuroscience. This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. In addition to the transcript encoding GDNF, two additional alternative transcripts encoding distinct proteins, referred to as astrocyte-derived trophic factors, have also been described. Mutations in this gene may be associated with Hirschsprung disease. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:200-800} |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
GDNF Rabbit pAb, BF405 conjugated(bs-1024R-BF405)-100ul
￥2980
