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- bs-0322R-BF350
- 2025年09月30日
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100ul
| 产品编号 | bs-0322R-BF350 |
| 英文名称 | AEBP1 Rabbit pAb, BF350 conjugated |
| 中文名称 | BF350标记的脂肪细胞增强结合蛋白1 |
| 英文别名 | AE binding protein 1; ACLP; Adipocyte enhancer binding protein 1; AEBP 1; AEBP1; Aortic carboxypeptidase like protein ACLP; Aortic carboxypeptidase like protein; FLJ33612; AEBP1_HUMAN; Adipocyte enhancer-binding protein 1; AE-binding protein 1; Aortic carboxypeptidase-like protein. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human AEBP1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Other factors Signal Transduction > Metabolism > Lipid metabolism |
| 亚基 | Interacts with GNG5, NFKBIA, MAPK1, MAPK3 and PTEN. May interact with calmodulin. Binds to DNA in vitro. |
| 亚细胞定位 | Isoform 1: Secreted._x000D_
Isoform 2: Cytoplasm (Probable). Nucleus (Probable). |
| 组织特异性 | Expressed in osteoblast and visceral fat. |
| 翻译后修饰 | Phosphorylated by MAPK1 in vitro. |
| 相似性 | Belongs to the peptidase M14 family._x000D_
Contains 1 F5/8 type C domain. |
| 功能 | May positively regulate MAP-kinase activity in adipocytes, leading to enhanced adipocyte proliferation and reduced adipocyte differentiation. May also positively regulate NF-kappa-B activity in macrophages by promoting the phosphorylation and subsequent degradation of I-kappa-B-alpha (NFKBIA), leading to enhanced macrophage inflammatory responsiveness. Can act as a transcriptional repressor. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of carboxypeptidase A protein family. The encoded protein may function as a transcriptional repressor and play a role in adipogenesis and smooth muscle cell differentiation. Studies in mice suggest that this gene functions in wound healing and abdominal wall development. Overexpression of this gene is associated with glioblastoma. [provided by RefSeq, May 2013]. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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AEBP1 Rabbit pAb, BF350 conjugated(bs-0322R-BF350)-100ul
￥2980
