ITGB5 Rabbit pAb, HRP conj.(bs-23987R-HRP)-100ul产品图

ITGB5 Rabbit pAb, HRP conj.(bs

-23987R-HRP)-100ul
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  • bs-23987R-HRP
  • 2026年10月17日
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    北京博奥森生物技术有限公司
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    • 规格：

      100ul

    产品编号bs-23987R-HRP
    英文名称Integrin beta 5 Rabbit pAb, HRP conjugated
    中文名称HRP标记的整合素β5抗体
    英文别名Integrin beta 5; Integrin beta-5; integrin, beta 5; ITB5_HUMAN; Itgb5; AA475909; AI874634; beta-5; beta5; ESTM23; [b]-5; [b]5; [b]5A; [b]5B) FLJ26658; ITGB 5; ITGB5;
    中文别名Integrin β5.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Integrin beta 5
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚基Heterodimer of an alpha and a beta subunit. Beta-5 associates with alpha-V. Interacts with MYO10. Interacts with DAB2.
    亚细胞定位Membrane; Single-pass type I membrane protein.
    相似性Belongs to the integrin beta chain family.
    Contains 1 PSI domain.
    Contains 1 VWFA domain.
    功能Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Integrins are important extracellular matrix (ECM) receptor proteins located on cell surfaces. They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit. Around 22 different integrins (different alpha/ beta subunit combinations) are found in nature. Integrins are generally present in high concentrations at the cell surface, but, unlike most other cell surface receptors, they bind ligands with very low affinity. Due to their weak individual binding, integrins need to cluster and bind in groups in order to effectively bind the ECM. Integrins bind many different ligands including laminin. Each integrin is made up of a large N terminal extracellular domain that binds the ECM ligand and a small C terminal cytoplasmic domain that mediates interaction with the actin cytoskeleton and signaling function.The integrin subunit beta 5 has only been associated with the alpha v subunit to form the alpha v beta 5 heterodimer. This integrin mediates cell adhesion to vitronectin and also recognizes fibronectin when the integrin is activated. This integrin is found in a variety of cells in most normal tissue.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

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    图标文献和实验
    相关实验

    • （共享）免疫单词缩写及翻译

      rabbit serum albumin 兔血清白蛋白 R-Sc Reed-Sternberg's cell 瑞-司氏细胞 Z/R Reinheit Zahl 光密度比值 SAV small agranular vesicle 无颗粒小泡 SBA soybean agglutinin 大豆凝集素 SC secretory component 分泌成份 SCV small clear vesicle 清亮小泡 SDS sodium

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